Route 40: An Unforgettable Journey Through the Heart of Argentina

The National Route 40, simply known as Route 40, is much more than a road: it’s an experience that traverses the very essence of Argentina. Stretching over 5,194 kilometers, this iconic highway runs north to south across the country, from La Quiaca in Jujuy to Cabo Vírgenes in Santa Cruz. It crosses 11 provinces, connecting dreamlike landscapes, diverse cultures, and unique destinations.

Provinces Crossed by Route 40

Route 40 passes through the provinces of Jujuy, Salta, Tucumán, Catamarca, La Rioja, San Juan, Mendoza, Neuquén, Río Negro, Chubut, and Santa Cruz. This route links some of the most emblematic regions of Argentina, offering travelers a variety of climates and geographies, from the valleys and gorges of the northwest to the glaciers and steppes of Patagonia.

Highlights Along Route 40

Route 40 passes near many tourist destinations that are must-sees for any adventurer:

•  Valle de la Luna Cusi Cusi (Jujuy): An impressive lunar landscape with unique rock formations and vibrant colors that seem out of this world.

• Mendoza Vineyards: Internationally renowned, they offer mountain views and unique wine-tasting experiences. Note: Do not continue driving after wine tasting!

• Bariloche (Río Negro): Known for its lakes, mountains, and year-round outdoor activities.



• El Chaltén (Santa Cruz): The national trekking capital, perfect for nature and adventure lovers.

• Perito Moreno Glacier (Santa Cruz): One of the world’s most impressive natural wonders.

Other nearby destinations include the Salinas Grandes in Jujuy, the Valley of the Moon in San Juan, Talampaya National Park in La Rioja, the cities of Belén in Catamarca, Esquel in Chubut, or San Juan in the province of the same name. Not to forget, the archaeological site Sacred City of the Quilmes in Tucumán and Los Alerces National Park in Chubut. Each one brings a unique perspective to the journey.

Three Must-See Spots on Route 40

1. Abra del Acay and Quebrada de las Flechas (Salta): Abra del Acay is the highest point on the route, over 4,800 meters above sea level. A challenge for the most daring. Continuing in Salta, the gravel road through Quebrada de las Flechas with its incredible mountain formations is another must-visit destination.

2. The Seven Lakes (Neuquén): The Route of the Seven Lakes is a spectacular journey connecting San Martín de los Andes and Villa La Angostura, surrounded by forests, mountains, and crystal-clear lakes. You can visit the Espejo, Correntoso, Villarino, Falkner, Hermoso, Machónico, and Lácar lakes, as well as other nearby lakes like the famous Nahuel Huapi Lake.

3. Cueva de las Manos (Santa Cruz): An archaeological site that features cave paintings over 9,000 years old, declared a UNESCO World Heritage Site.

Where to Start the Journey

Route 40 can be traveled in any direction, depending on the traveler’s interests:

• From the North (La Quiaca): Ideal for those wanting to explore the cultural and archaeological richness of the northwest.
• From the South (Cabo Vírgenes): Perfect for lovers of Patagonian landscapes and extreme adventures.

Time Needed to Travel the Route

The time required to travel Route 40 depends on the trip’s length and planned stops:

• Northern Section: From La Quiaca to Mendoza, approximately 10 days if exploring major attractions.
• Southern Section: From Mendoza to Cabo Vírgenes, at least 15 days, as distances are greater and landscapes often call for frequent stops.
• Full Route: For a complete experience of Route 40, a minimum of 3 to 4 weeks is recommended.

Tips for Travelers

• Planning: Research the conditions of each section in advance, as some stretches may be gravel roads or affected by weather.
• Vehicle: A sturdy vehicle, preferably a 4x4, is recommended, especially in the north and Patagonia.
• Fuel and Supplies: Make sure to carry enough fuel, water, and food, as there are long stretches without services.



Route 40 is more than a road; it’s a journey through the soul of Argentina. Every kilometer tells a story, every landscape leaves an unforgettable mark. Get ready for the adventure of a lifetime!